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Fabrication of a Flexible Amperometric Glucose Sensor Using Additive Processes

ScholarsArchive at Oregon State University

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Title Fabrication of a Flexible Amperometric Glucose Sensor Using Additive Processes
Names Du, Xiaosong (creator)
Durgan, Christopher J. (creator)
Matthews, David J. (creator)
Motley, Joshua R. (creator)
Tan, Xuebin (creator)
Pholsena, Kovit (creator)
Árnadóttir, Líney (creator)
Castle, Jessica R. (creator)
Jacobs, Peter G. (creator)
Cargill, Robert S. (creator)
Ward, W. Kenneth (creator)
Conley, John F., Jr. (creator)
Hermana, Gregory S. (creator)
Date Issued 2015-02-18 (iso8601)
Note This is the publisher’s final pdf. The published article is copyrighted by the Electrochemical Society and can be found at: http://jss.ecsdl.org/.
Abstract This study details the use of printing and other additive processes to fabricate a novel amperometric glucose sensor. The sensor was
fabricated using a Au coated 12.7 μm thick polyimide substrate as a starting material, where micro-contact printing, electrochemical
plating, chloridization, electrohydrodynamic jet (e-jet) printing, and spin coating were used to pattern, deposit, chloridize, print, and
coat functional materials, respectively. We have found that e-jet printing was effective for the deposition and patterning of glucose
oxidase inks with lateral feature sizes between ∼5 to 1000 μm in width, and that the glucose oxidase was still active after printing.
The thickness of the permselective layer was optimized to obtain a linear response for glucose concentrations up to 32 mM and
no response to acetaminophen, a common interfering compound, was observed. The use of such thin polyimide substrates allow
wrapping of the sensors around catheters with high radius of curvature ∼250 μm, where additive and microfabrication methods may
allow significant cost reductions.
Genre Article
Identifier Du, X., Durgan, C. J., Matthews, D. J., Motley, J. R., Tan, X., Pholsena, K., ... & Herman, G. S. (2015). Fabrication of a Flexible Amperometric Glucose Sensor Using Additive Processes. ECS Journal of Solid State Science and Technology, 4(4), P3069-P3074. doi:10.1149/2.0101504jss

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