Record Details

Finding Our Way through Phenotypes

ScholarsArchive at Oregon State University

Field Value
Title Finding Our Way through Phenotypes
Names Deans, Andrew R. (creator)
Lewis, Suzanna E. (creator)
Huala, Eva (creator)
Cooper, Laurel D. (creator)
Jaiswal, Pankaj (creator)
et al. (creator)
Date Issued 2015-01-06 (iso8601)
Note This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by the Public Library of Science. The published article can be found at: http://journals.plos.org/plosbiology/.
Abstract Despite a large and
multifaceted effort to understand
the vast landscape of phenotypic
data, their current form inhibits
productive data analysis. The lack
of a community-wide, consensus-based,
human- and machine-interpretable
language for describing
phenotypes and their genomic and
environmental contexts is perhaps
the most pressing scientific bottleneck
to integration across many
key fields in biology, including
genomics, systems biology, development,
medicine, evolution, ecology,
and systematics. Here we
survey the current phenomics landscape,
including data resources and
handling, and the progress that has
been made to accurately capture
relevant data descriptions for phenotypes.
We present an example of
the kind of integration across
domains that computable phenotypes
would enable, and we call
upon the broader biology community,
publishers, and relevant funding
agencies to support efforts to
surmount today’s data barriers and
facilitate analytical reproducibility.
Genre Article
Access Condition http://creativecommons.org/licenses/by/3.0/us/
Identifier Deans, A. R., Lewis, S. E., Huala, E., Anzaldo, S. S., Ashburner, M., et al. (2015). Finding Our Way through Phenotypes. PLoS Biology, 13(1), e1002033. doi:10.1371/journal.pbio.1002033

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