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VitisCyc: a metabolic pathway knowledgebase for grapevine (Vitis vinifera)

ScholarsArchive at Oregon State University

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Title VitisCyc: a metabolic pathway knowledgebase for grapevine (Vitis vinifera)
Names Naithani, Sushma (creator)
Raja, Rajani (creator)
Waddell, Elijah N. (creator)
Elser, Justin (creator)
Gouthu, Satyanarayana (creator)
Deluc, Laurent G. (creator)
Jaiswal, Pankaj (creator)
Date Issued 2014-12-09 (iso8601)
Note This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by the Frontiers Research Foundation. The published article can be found at: http://www.frontiersin.org/Plant_Science.
Abstract We have developed VitisCyc, a grapevine-specific metabolic pathway database that allows
researchers to (i) search and browse the database for its various components such as
metabolic pathways, reactions, compounds, genes and proteins, (ii) compare grapevine
metabolic networks with other publicly available plant metabolic networks, and (iii)
upload, visualize and analyze high-throughput data such as transcriptomes, proteomes,
metabolomes etc. using OMICs-Viewer tool. VitisCyc is based on the genome sequence
of the nearly homozygous genotype PN40024 of Vitis vinifera “Pinot Noir” cultivar with
12X v1 annotations and was built on BioCyc platform using Pathway Tools software
and MetaCyc reference database. Furthermore, VitisCyc was enriched for plant-specific
pathways and grape-specific metabolites, reactions and pathways. Currently VitisCyc
harbors 68 super pathways, 362 biosynthesis pathways, 118 catabolic pathways, 5
detoxification pathways, 36 energy related pathways and 6 transport pathways, 10,908
enzymes, 2912 enzymatic reactions, 31 transport reactions and 2024 compounds.
VitisCyc, as a community resource, can aid in the discovery of candidate genes and
pathways that are regulated during plant growth and development, and in response to
biotic and abiotic stress signals generated from a plant’s immediate environment. VitisCyc
version 3.18 is available online at http://pathways.cgrb.oregonstate.edu.
Genre Article
Access Condition http://creativecommons.org/licenses/by/3.0/us/
Topic Grape
Identifier Naithani, S., Raja, R., Waddell, E. N., Elser, J., Gouthu, S., Deluc, L. G., & Jaiswal, P. (2014). VitisCyc: a metabolic pathway knowledgebase for grapevine (Vitis vinifera). Frontiers in Plant Science, 5, 644. doi:10.3389/fpls.2014.00644

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