Record Details

Primary Intestinal and Vertebral Chordomas in Laboratory Zebrafish (Danio rerio)

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Field Value
Title Primary Intestinal and Vertebral Chordomas in Laboratory Zebrafish (Danio rerio)
Names Cooper, Timothy K. (creator)
Murray, Katrina N. (creator)
Spagnoli, Sean (creator)
Spitsbergen, Jan M. (creator)
Date Issued 2014-06-09 (iso8601)
Note This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American College of Veterinary Pathologists and published by Sage Publications. It can be found at: http://intl-vet.sagepub.com/.
Abstract Chordomas are uncommon neoplasms arising from notochord remnants, most commonly
occurring in the axial skeleton. Extraskeletal soft tissue chordomas are rare primary tumors, and
primary intestinal chordomas have not been reported. Herein we report 24 cases of spontaneous
primary intestinal chordomas in zebrafish, as well as 9 spontaneous vertebral chordomas. Both
intestinal and vertebral tumors showed invasive behavior, although more commonly in the latter. In all
cases of primary intestinal chordomas, there was no axial or peripheral skeletal or other non-visceral
involvement. Although uncommon, intestinal chordomas represent a unique background lesion in aged
zebrafish.
Genre Article
Topic Chordomas
Identifier Cooper, T. K., Murray, K. N., Spagnoli, S., & Spitsbergen, J. M. (2014). Primary Intestinal and Vertebral Chordomas in Laboratory Zebrafish (Danio rerio). Veterinary Pathology, 0300985814537531. doi:10.1177/0300985814537531

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