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Genetic resources for advanced biofuel production described with the Gene Ontology

ScholarsArchive at Oregon State University

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Title Genetic resources for advanced biofuel production described with the Gene Ontology
Names Torto-Alalibo, Trudy (creator)
Purwantini, Endang (creator)
Lomax, Jane (creator)
Setubal, João C. (creator)
Mukhopadhyay, Biswarup (creator)
Tyler, Brett M. (creator)
Date Issued 2014-10-10 (iso8601)
Note This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by the Frontiers Research Foundation. The published article can be found at: http://www.frontiersin.org/Microbiology. Supplementary Material can be found at: http://www.frontiersin.org/journal/10.3389/fmicb.2014.00528/.
Abstract Dramatic increases in research in the area of microbial biofuel production coupled with
high-throughput data generation on bioenergy-related microbes has led to a deluge of
information in the scientific literature and in databases. Consolidating this information and
making it easily accessible requires a unified vocabulary. The Gene Ontology (GO) fulfills that
requirement, as it is a well-developed structured vocabulary that describes the activities
and locations of gene products in a consistent manner across all kingdoms of life. The
Microbial ENergy processes Gene Ontology (http://www.mengo.biochem.vt.edu) project
is extending the GO to include new terms to describe microbial processes of interest
to bioenergy production. Our effort has added over 600 bioenergy related terms to the
Gene Ontology. These terms will aid in the comprehensive annotation of gene products
from diverse energy-related microbial genomes. An area of microbial energy research
that has received a lot of attention is microbial production of advanced biofuels. These
include alcohols such as butanol, isopropanol, isobutanol, and fuels derived from fatty
acids, isoprenoids, and polyhydroxyalkanoates. These fuels are superior to first generation
biofuels (ethanol and biodiesel esterified from vegetable oil or animal fat), can be generated
from non-food feedstock sources, can be used as supplements or substitutes for gasoline,
diesel and jet fuels, and can be stored and distributed using existing infrastructure. Here
we review the roles of genes associated with synthesis of advanced biofuels, and at the
same time introduce the use of the GO to describe the functions of these genes in a
standardized way.
Genre Article
Access Condition http://creativecommons.org/licenses/by/3.0/us/
Topic Gene Ontology
Identifier Torto-Alalibo, T., Purwantini, E., Lomax, J., Setubal, J. C., Mukhopadhyay, B., & Tyler, B. M. (2014). Genetic resources for advanced biofuel production described with the Gene Ontology. Frontiers in Microbiology, 5, 528. doi:10.3389/fmicb.2014.00528

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