Record Details
Gramene QTL database: development, content and applications
ScholarsArchive at Oregon State University
| Field | Value |
|---|---|
| Title | Gramene QTL database: development, content and applications |
| Names |
Ni, Junjian
(creator) Pujar, Anuradha (creator) Youens-Clark, Ken (creator) Jaiswal, Pankaj (creator) et al. (creator) |
| Date Issued | 2009-05-08 (iso8601) |
| Note | This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by Oxford University Press. The published article can be found at: http://database.oxfordjournals.org/. |
| Abstract | Gramene is a comparative information resource for plants that integrates data across diverse data domains. In this article, we describe the development of a quantitative trait loci (QTL) database and illustrate how it can be used to facilitate both the forward and reverse genetics research. The QTL database contains the largest online collection of rice QTL data in the world. Using flanking markers as anchors, QTLs originally reported on individual genetic maps have been systematically aligned to the rice sequence where they can be searched as standard genomic features. Researchers can determine whether a QTL co-localizes with other QTLs detected in independent experiments and can combine data from multiple studies to improve the resolution of a QTL position. Candidate genes falling within a QTL interval can be identified and their relationship to particular phenotypes can be inferred based on functional annotations provided by ontology terms. Mutations identified in functional genomics populations and association mapping panels can be aligned with QTL regions to facilitate fine mapping and validation of gene–phenotype associations. By assembling and integrating diverse types of data and information across species and levels of biological complexity, the QTL database enhances the potential to understand and utilize QTL information in biological research. |
| Genre | Article |
| Access Condition | http://creativecommons.org/licenses/by-nc/3.0/us/ |
| Identifier | Ni, J., Pujar, A., Youens-Clark, K., Yap, I., Jaiswal, P., Tecle, I., ... & McCouch, S. (2009). Gramene QTL database: development, content and applications. Database, 2009. doi:10.1093/database/bap005 |
