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A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students

ScholarsArchive at Oregon State University

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Title A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students
Names Jordan, Tuajuanda C. (creator)
Burnett, Sandra H. (creator)
Carson, Susan (creator)
Caruso, Steven M. (creator)
Clase, Kari (creator)
DeJong, Randall J. (creator)
Dennehy, John J. (creator)
Denver, Dee R. (creator)
Dunbar, David (creator)
Elgin, Sarah C. R. (creator)
Findley, Ann M. (creator)
Gissendanner, Chris R. (creator)
Golebiewska, Urszula P. (creator)
Guild, Nancy (creator)
Hartzog, Grant A. (creator)
Grillo, Wendy H. (creator)
Hollowell, Gail P. (creator)
Hughes, Lee E. (creator)
Johnson, Allison (creator)
King, Rodney A. (creator)
Lewis, Lynn O. (creator)
Li, Wei (creator)
Rosenzweig, Frank (creator)
Rubin, Michael R. (creator)
Saha, Margaret S. (creator)
Sandoz, James (creator)
Shaffer, Christopher D. (creator)
Taylor, Barbara (creator)
Temple, Louise (creator)
Vazquez, Edwin (creator)
Ware, Vassie C. (creator)
Barker, Lucia P. (creator)
Bradley, Kevin W. (creator)
Jacobs-Sera, Deborah (creator)
Pope, Welkin H. (creator)
Russell, Daniel A. (creator)
Cresawn, Steven G. (creator)
Lopatto, David (creator)
Bailey, Cheryl P. (creator)
Hatfull, Graham F. (creator)
Date Issued 2014-02-04 (iso8601)
Note This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by American Society for Microbiology. The published article can be found at: http://mbio.asm.org/.
Abstract Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We
have developed a general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a
research course for first-year undergraduate students focused on bacteriophage discovery and genomics. The course is situated
within a broader scientific context aimed at understanding viral diversity, such that faculty and students are collaborators with
established researchers in the field. The Howard Hughes Medical Institute (HHMI) Science Education Alliance Phage Hunters
Advancing Genomics and Evolutionary Science (SEA-PHAGES) course has been widely implemented and has been taken by over
4,800 students at 73 institutions. We show here that this alliance-sourced model not only substantially advances the field of
phage genomics but also stimulates students’ interest in science, positively influences academic achievement, and enhances persistence
in science, technology, engineering, and mathematics (STEM) disciplines. Broad application of this model by integrating
other research areas with large numbers of early-career undergraduate students has the potential to be transformative in science
education and research training.
IMPORTANCE: Engagement of undergraduate students in scientific research at early stages in their careers presents an opportunity
to excite students about science, technology, engineering, and mathematics (STEM) disciplines and promote continued interests
in these areas. Many excellent course-based undergraduate research experiences have been developed, but scaling these to a
broader impact with larger numbers of students is challenging. The Howard Hughes Medical Institute (HHMI) Science Education
Alliance Phage Hunting Advancing Genomics and Evolutionary Science (SEA-PHAGES) program takes advantage of the
huge size and diversity of the bacteriophage population to engage students in discovery of new viruses, genome annotation, and
comparative genomics, with strong impacts on bacteriophage research, increased persistence in STEM fields, and student selfidentification
with learning gains, motivation, attitude, and career aspirations.
Genre Article
Access Condition http://creativecommons.org/licenses/by-nc-sa/3.0/us/
Identifier Jordan, T. C., Burnett, S. H., Carson, S., Caruso, S. M., Clase, K., DeJong, R. J., ... & Hatfull, G. F. (2014). A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students. mBio, 5(1), e01051-13. doi:10.1128/mBio.01051-13

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