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Dosimetry considerations in the irradiation of biological populations

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Title Dosimetry considerations in the irradiation of biological populations
Names Denovan, James Thomas (creator)
Elder, Robert L. (advisor)
Date Issued 1967-07-14 (iso8601)
Note Graduation date: 1968
Abstract The effects of changes in dosimetry conditions on the radiation
sensitivity of a constant biological population were determined.
The organism used for this study was the strain B of
Escherichia coli. The percentage survivals of these cells in an
aqueous solution were determined at the same total exposure with
different quality x-rays. The total absorbed dose was measured as
a function of x-ray quality. During all irradiations the focal-target
distance, tube current, field size, and biological population were held
constant. The distribution of radiation to which the organisms were
exposed was kept constant by the use of a rotating exposure platform.
This platform was constructed of materials such that the contributions
from backscatter would be minimized.
The results indicated that the test organism was more sensitive
to low energy x-rays than to high energy x-rays in the range from 15 keV to 145 keV effective energy. However, at low effective x-ray
energies the absorbed dose was found to be lower than at higher
effective energies. This was explained by differences in the specific
ionization of different energy x-rays in aqueous solutions.
It was concluded that dosimetry conditions are a significant
factor in the determination of the radiation sensitivity of E. coli B.
The results indicate the necessity of reporting accurate exposure
conditions when studying the radiation response of biological populations.
Genre Thesis/Dissertation
Topic Radiation -- Dosage
Identifier http://hdl.handle.net/1957/47230

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