Record Details
Preparation and comparative solubility of poly-L-tyrosyl lysozyme and poly-O-methyl-L-tyrosyl lysozyme
ScholarsArchive at Oregon State University
| Field | Value |
|---|---|
| Title | Preparation and comparative solubility of poly-L-tyrosyl lysozyme and poly-O-methyl-L-tyrosyl lysozyme |
| Names |
Venier, Lynn Corrine
(creator) Becker, Robert R. (advisor) |
| Date Issued | 1966-08-18 (iso8601) |
| Note | Graduation date: 1967 |
| Abstract | In order to examine some possible tyrosyl interactions, poly-tyrosyl lysozyme and poly-O-methyltyrosyl lysozyme were prepared and their solubilities were compared. Both derivatives exhibited similar pH dependent solubilities, showing a minimum solubility at about pH 8. Their solubilities varied with temperature, having a positive enthalpy of solution. The effect of a lyotropic series of ions on the solubility of these lysozyme derivatives followed the same order in their ability to solubilize these derivatives as their ability to disaggregate proteins. The tyrosyl and O-methyltyrosyl lysozyme aggregations are believed to be due to interactions which cannot be delineated as singly hydrophobic, ionic or polar interactions. |
| Genre | Thesis/Dissertation |
| Topic | Lysozyme |
| Identifier | http://hdl.handle.net/1957/47091 |
