Record Details
The effect of streptomycin on proline synthesis in Escherichia coli
ScholarsArchive at Oregon State University
| Field | Value |
|---|---|
| Title | The effect of streptomycin on proline synthesis in Escherichia coli |
| Names |
Couch, David Bruce
(creator) Baich, Annette (advisor) |
| Date Issued | 1967-11-27 (iso8601) |
| Note | Graduation date: 1968 |
| Abstract | The effect of streptomycin on an early reaction of proline synthesis, the production of glutamic-γ-semialdehyde, in resting cell suspensions of antibiotic-sensitive, resistant, and dependent strains of Escherichia coli was examined, and the effect on glutamic-γ-semialdehyde production was found to correspond to the growth response of the organisms to streptomycin. Inhibition of glutamic-γ-semialdehyde production in sensitive strains was found not to be caused by streptomycin-induced changes in permeability to substrate or product of the reaction. The effects of pH, ionic strength, and the presence of purines, pyrimidines, and nucleotides on streptomycin action were examined, and possibilities for the mode and site of streptomycin action are discussed. |
| Genre | Thesis/Dissertation |
| Topic | Escherichia coli |
| Identifier | http://hdl.handle.net/1957/47094 |
