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An histochemical study of the changing patterns of glycogen distribution in the uterus of the early pregnant and lactating golden hamster (Mesocricetus auratus Waterhouse)

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Title An histochemical study of the changing patterns of glycogen distribution in the uterus of the early pregnant and lactating golden hamster (Mesocricetus auratus Waterhouse)
Names Wicklund, Thomas Glen (creator)
Hillemann, Howard H. (advisor)
Date Issued 1968-08-08 (iso8601)
Note Graduation date: 1969
Abstract This study deals with the histochemical identification of the
changing patterns of glycogen in the uterus of the early pregnant and
lactating golden hamster (Mesocricetus auratus Waterhouse). The uterus of the hamster representing days one through five of gestation,
and one through ten, twelve, and fourteen of lactation, provided the
data for this study. Diastase digestion was used on alternate sections
of the uterus prior to staining with periodic acid-Schiff, and
these sections were compared with adjacent stained sections (untreated
with diastase) for assessing the glycogen pattern. The
presence and amounts of glycogen in the uterine tissues of both the
pregnant and lactating animals are inconsistent. The outer longitudinal
myometrium of the pregnancy uteri generally contains more
glycogen than the inner circular myometrium, whereas these two
layers in the lactation uteri usually contain equal amounts. Granular
glycogen in the endometrium was seen only during gestation and
solely on the fifth day, on which it is restricted to the locular level
of the uterus and in very dense deposits. The uterine epithelium
proper contains granular glycogen in small amounts on some days of
gestation, but none occurs in the lactation uteri. Although the associated
basement membrane never contains granular glycogen, the
diffuse form is present but rather inconsistently. The epithelial
border of the pregnancy uterus contains patches of glycogen granules
with greater frequency than does that of the lactation uterus. Seldom
does glycogen occur in the uterine lumen but when it does, it is
always in patches. The epithelium and lumen of the uterine glands
contain small amounts of granular glycogen on some days of pregnancy
whereas, with one exception, neither of these areas in the
lactation uteri have granules. Diffuse glycogen in varying amounts
commonly occurs in the basement membrane associated with the
uterine glands. Whereas the tunic of the veins during pregnancy
contains more granular glycogen than does the tunica media of the
arteries, only diffuse glycogen was noted in these tunics of the
lactation uteri and in equal amounts. A comparison is made between
current observations on the hamster and those made by others
not only in the hamster but also on other species.
Genre Thesis/Dissertation
Topic Hamsters
Identifier http://hdl.handle.net/1957/46553

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