Record Details
Field | Value |
---|---|
Title | Electron Capture, Collision-Induced, and Electron Capture-Collision Induced Dissociation in Q-TOF |
Names |
Voinov, Valery G.
(creator) Deinzer, Max L. (creator) Beckman, Joseph S. (creator) Barofsky, Douglas F. (creator) |
Date Issued | 2011-04 (iso8601) |
Note | This is an author's manuscript. The published article is copyrighted by Springer and can be found at: http://link.springer.com/journal/13361. |
Abstract | Recently, we demonstrated that a radio-frequency-free electromagnetostatic (RF-free EMS) cell could be retrofitted into a triple quad mass spectrometer to allow electron-capture dissociation (ECD) without the aid of cooling gas or phase-specific electron injection into the cell [1-2]. Subsequently, we used our RF-free EMS cell in the same instrument platform to demonstrate ECD occurring in the same space and at the same time with collision-induced dissociation (CID) to produce golden pairs and even triplets from peptides [3]. In this report, we demonstrate that ECD and CID product-ion mass spectra can be recorded at high resolution with flexible control of fragmentation processes using a newly designed cell installed in a hybrid Q-TOF tandem mass spectrometer. |
Genre | Article |
Topic | Electron capture dissociation |
Identifier | Voinov, V. G., Deinzer, M. L., Beckman, J. S., & Barofsky, D. F. (2011). Electron capture, collision-induced, and electron capture-collision induced dissociation in Q-TOF. Journal of The American Society for Mass Spectrometry, 22(4), 607-611. doi:10.1007/s13361-010-0072-x |