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A method of controlling the left ventricular wall stress of the human heart

ScholarsArchive at Oregon State University

Field Value
Title A method of controlling the left ventricular wall stress of the human heart
Names Sohrab, Soheil (creator)
Saugen, John L. (advisor)
Date Issued 1969-12-18 (iso8601)
Note Graduation date: 1970
Abstract In this thesis a method is presented for maintaining the left
ventricular wall stress of the human heart at a constant level during
the systole (active portion of the heart's cycle). This constant stress
level makes it possible to take isotonic measurements on the heart
muscles.
The left ventricle of the human heart is modeled on a hybrid
computer. To accomplish this task certain assumptions as to the
shape and muscle characteristics of the left ventricle are made; then
the relations for stress and pressure are obtained. The
simulating force for this active left ventricle is a curve, simulated
by a Diode Function Generator, representing the muscle characteristics
of the left ventricle as a function of time. This model substitutes
for the portion of an active heart needed to design the
control device.
With this model of the left ventricle, a control device is
developed, using an analog computer, which acts as a pump controlling
the amount of fluid in the left ventricle during the systole. This
pump extracts the fluid from the cavity when the stress rises above
the desired level and reinjects the fluid into the cavity when the
stress falls below this level.
The control device consists of a piston and cylinder assembly
with a preloaded spring behind the piston. An electromagnetic feedback
control may be used to maintain the stress level. It is not
essential, however, since this control system accomplishes the same
purpose as a passive device by adjusting the system parameters. The
parameter values are given in Chapter III of this thesis. This control
device is applicable to any left ventricle within the range of 60
to 150 ml.
Another possible future application of this control device is its
use as an auxiliary pump to control the pressure in the left ventricle
of a failing human heart. This device could be connected to the aorta.
This use of the control device is theoretical and has not yet been
tested.
Genre Thesis/Dissertation
Topic Cardiology -- Research
Identifier http://hdl.handle.net/1957/46234

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